STRAIN CHARACTERISATION AND BASIC PROBIOTIC PROPERTIES
Basic probiotic properties, such as the ability to survive digestion and adhere to the cell lining, are essential to the health supporting effects of probiotic strains.
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Additionally, their growth properties and metabolic properties are of high importance for production process and may significantly impact their health promoting properties.
At ACARYON, a wide range of standardised assays are available to characterise your strains and analyse or optimise their basic probiotic properties.
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Our experts are here to help you uncover the full potential of your strains.
Have a non-binding consultation with one of our experts to find out the best solution for your needs.
Book a discussion slot or contact us.
Antibiotics resistance profile
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Knowing the antibiotic resistance profile of your probiotic strain(s) is crucial to ensure its safety and effectiveness.
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The resistance of your strains to a broad range of antibiotics is analysid using Minimum Inhibitory Concentration (MIC) Testing.
Growth properties
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Understanding the growth properties of your probiotic strain(s) is essential to optimise its performance, stability and survival.
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The growth properties of your strains may be analysed under a broad range of conditions and media.
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On demand, an optimal medium composition can be developed to ensure optimal growth and/or to ensure the optimal development of specific properties.
Metabolite production
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The metabolic properties of your probiotic strain(s) are key to its ability to enhance gut health and support overall well-being.
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The production of metabolites, like short chain fatty acids, lactate etc., is analysed throughout the growth in different media/conditions.
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If needed, we may run subcloning experiments to select subclones with improved metabolite production capacities.
Resistance to gastrointestinal conditions
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Resistance to gastrointestinal conditions is a main condition for probiotic strains to provide their beneficial effects.
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Based on established and validated methods, we analyse the resistance of your strains to gastrointestinal conditions (gastric juice, bile salt, ileum juice and gut juices).
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If needed, we can develop culture conditions to enhance the resistance of your strains.
Adhesion properties
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Adhesion to host cells is key for probiotic strains to provide their beneficial effects.
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We have established adhesion assays based on a wide range of cell lines, including gut cells, gastric cells, vaginal cells etc.
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If needed, we can develop culture conditions or run subcloning experiments to improve the adhesion properties of your strains.
Have a non-binding consultation with one of our experts to find out the best solution for your needs. Book a discussion slot or contact us.
